Importance The United States has invested substantially in screening and brief intervention
for illicit drug use and prescription drug misuse, based in part on evidence of efficacy for …

Objective. —To assess the effect of an individualized treatment regimen on the intensity and
duration of medication treatment for alcohol withdrawal. Design. —A randomized double-…

Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of …

Objective To study the association between benzodiazepine prescribing patterns including
dose, type, and dosing schedule and the risk of death from drug overdose among US …

BACKGROUND Unhealthy alcohol use is prevalent but under-diagnosed in primary care
settings. OBJECTIVE To validate, in primary care, a single-item screening test for unhealthy …

Background People who inject drugs (PWID) have limited engagement in healthcare services
and report frequent experiences of stigma and mistreatment when accessing services. …

Issues. Although screening and brief intervention (BI) in the primary‐care setting reduces
unhealthy alcohol use, its efficacy among patients with dependence has not been established. …

Importance People with substance dependence have health consequences, high health
care utilization, and frequent comorbidity but often receive poor-quality care. Chronic care …

Background Drug use (illicit drug use and nonmedical use of prescription drugs) is common
but underrecognized in primary care settings. We validated a single-question screening test …

Alcohol use is common among people living with human immunodeficiency virus ( HIV ). In
this narrative review, we describe literature regarding alcohol's impact on transmission, care, …