Chronic kidney disease (CKD) is a global health burden with a high economic cost to health
systems and is an independent risk factor for cardiovascular disease (CVD). All stages of …

Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

Background The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …

Background Anticoagulants are more effective than antiplatelet agents at reducing stroke
risk in patients with atrial fibrillation, but whether this benefit outweighs the increased risk of …

Purpose Venous thromboembolism (VTE) is common in patients with cancer. Long-term daily
subcutaneous low molecular weight heparin has been standard treatment for such patients…

: Many techniques for management of hypertrophic scars and keloids have been proven
through extensive use, but few have been supported by prospective studies with adequate …

Background The BNT162b2 mRNA (Pfizer–BioNTech) and ChAdOx1 nCoV-19 (Oxford–AstraZeneca)
COVID-19 vaccines have shown high efficacy against disease in phase 3 clinical …

Background There are few primary care studies of the COVID-19 pandemic. We aimed to
identify demographic and clinical risk factors for testing positive for severe acute respiratory …

Background Control of blood pressure is a key component of cardiovascular disease
prevention, but is difficult to achieve and until recently has been the sole preserve of health …

Background A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in
patients not admitted to hospital, but effectiveness in high-risk individuals is unknown. We …