Summary of Outcome Changes of Included Studies (n = 110)
| Study Characteristic | No. | % (95% CI) |
|---|---|---|
| Note: Studies could have multiple changes. | ||
| Primary outcomes | ||
| No change | 76 | 69 (60–77) |
| Change | 34 | 31 (23–40) |
| Change by addition | 10 | – |
| Change by promotion from secondary | 3 | – |
| Change by deletion | 20 | – |
| Change by demotion to secondary | 6 | – |
| Secondary outcomes | ||
| No change | 33 | 30 (22–39) |
| Change | 77 | 70 (61–78) |
| Change by addition | 54 | – |
| Change by demotion from primary | 5 | – |
| Change by deletion | 48 | – |
| Change by promotion to primary | 3 | – |