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Research ArticleOriginal Research

Airway Obstruction and Bronchodilator Responsiveness in Adults With Acute Cough

Saskia van Vugt, Lidewij Broekhuizen, Nicolaas Zuithoff, Christopher Butler, Kerenza Hood, Samuel Coenen, Herman Goossens, Paul Little, Jordi Almirall, Francesco Blasi, Slawomir Chlabicz, Mel Davies, Maciek Godycki-Cwirko, Helena Hupkova, Janko Kersnik, Michael Moore, Tom Schaberg, An De Sutter, Antoni Torres, Theo Verheij and On behalf of the GRACE Project Group
The Annals of Family Medicine November 2012, 10 (6) 523-529; DOI: https://doi.org/10.1370/afm.1416
Saskia van Vugt
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, MSc
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Lidewij Broekhuizen
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Nicolaas Zuithoff
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MSc, PhD
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Christopher Butler
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Kerenza Hood
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
PhD
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Samuel Coenen
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Herman Goossens
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Paul Little
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Jordi Almirall
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Francesco Blasi
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Slawomir Chlabicz
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Mel Davies
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
RN, PhD
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Maciek Godycki-Cwirko
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Helena Hupkova
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Janko Kersnik
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Michael Moore
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Tom Schaberg
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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An De Sutter
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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Antoni Torres
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
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Theo Verheij
University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)
MD, PhD
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University Medical Center Utrecht, Julius Center for Health, Sciences and Primary Care, Utrecht, the Netherlands (van Vugt, Broekhuizen, Zuithoff, Verheij); Cardiff University, Institute of Primary Care and Public Health Medicine, Cardiff, Wales, United Kingdom (Butler, Hood); University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Antwerp, Belgium (Coenen, Goossens); Primary Care Medical Group, University of Southampton Medical School, Southampton, United Kingdom (Little, Moore); Intensive Care Unit, Hospital de Mataro, Mataro, Spain (Almirall); Respiratory Medicine Section, Dipar-timento Toraco-Polmonare e Cardiocircolatorio, University of Milan, IRCCS Fondazione Cà Granda, Milan, Italy (Blasi); Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland (Chlabicz); Ely Bridge Surgery, Ely Bridge Surgery, Cardiff, United Kingdom (Davies); Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland (Godycki-Cwirko); Institute of Microbiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia (Hupkova); Zdravstveni dom Jesenice and University of Ljubljana Medical School, Slovenia (Kersnik); Zentrum für Pneumologie, Diakoniekrankenhaus Rotenburg, Rotenburg, Germany (Schaberg); Ghent University, University Hospital, Ghent, Belgium (De Sutter); Servei de Pneumologia, Institut Clinic del Torax, Barcelona, Spain (Torres)

Supplemental Table & Figure

Supplemental Table 1. Missing or Incomplete Spirometry Results per Country; Supplemental Figure 1. Prevalence of airway obstruction and bronchodilator responsiveness in patients with acute cough (n = 3,105), per country (shown with mean age and proportion of current or past smokers).

Files in this Data Supplement:

  • Supplemental data: Table 1 - PDF file, 1 page, 156 KB
  • Supplemental data: Figure - PDF file, 1 page, 623 KB

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